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PubMed · 2629960

[Current trends in experimental peripheral nerve regeneration].

G Lejeune·M Foidart·A M Severyns·P Delree·A Lejeune·D Clermont·G Rocoux
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Abstract

Large posttraumatic defects in the peripheral nervous system need to discover methods to solve the demand of nerve grafts. There is no definite answer now. The authors present a model for nervous regeneration studies. Experiments are performed in the Wistar rat. A venous isograft is used to bridge defects of various size in a divided rat sciatic nerve. The venous tube is a guide for axonal regeneration. In one series, the tube is filled with physiological saline and, in a second one, neonatal Schwann cells are injected in the venous isograft. Results recorded are a combination of quantitative methods: neurophysiology and morphometry. The injection of neonatal Schwann cells is able to stimulate nerve regeneration but not completely.

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AnimalsNerve RegenerationRatsRats, Inbred StrainsSchwann CellsSciatic NerveVeinsEnglish AbstractJournal Article

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G Lejeune, M Foidart, A M Severyns, P Delree, A Lejeune, D Clermont, G Rocoux. 1989. [Current trends in experimental peripheral nerve regeneration].. https://pubmed.ncbi.nlm.nih.gov/2629960/

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