Prolonged hyperprolactinemia in preterm infants.

M Perlman; J Schenker; M Glassman; M Ben-david

doi:10.1210/jcem-47-4-894

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Prolonged hyperprolactinemia in preterm infants.

M Perlman·J Schenker·M Glassman·M Ben-david

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Abstract

Serum PRL levels were followed serially in full term (FT; 39-41 weeks) and preterm (PT; 30-32 weeks) infants, from birth to 12 and 20 postnatal weeks, respectively. Values were higher in FT infants than in PT infants on day 1 after birth (267 +/- 20 vs. 156 +/- 8 ng/ml) but were similar in both by the age of 2-4 weeks (69 +/- 8 vs. 69 +/- 6 ng/ml). Between the ages of 4-12 weeks, the serum PRL in FT infants fell to near adult levels (24 +/- 2 ng/ml), but this fall was seen much later in PT infants, between 12-20 weeks postnatally (23 +/- 2 ng/ml). When values in FT and PT infants were compared at parallel postmenstrual ages in contradistinction to postnatal ages, a similar course of PRL was discernable in both groups. These data may provide indirect evidence for the establishment and maturation of inhibition of PRL secretion (i.e. PRL-inhibitory factor production) postnatally, between 44-52 weeks postmenstrually.

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Aging Humans Infant, Newborn Infant, Premature Prolactin Comparative Study Journal Article

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M Perlman, J Schenker, M Glassman, M Ben-david. 1978. Prolonged hyperprolactinemia in preterm infants.. https://doi.org/10.1210/jcem-47-4-894

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