Effect of age on epidermal immune function.

D N Sauder

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PubMed · 2645993

Effect of age on epidermal immune function.

D N Sauder

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Abstract

Like other systems in the body, the immune system deteriorates with age. Age-related changes in epidermal immune function include morphologic and functional changes in Langerhans cells, decreased production and response to epidermal thymocyte-activating factor (ETAF), and altered allergic contact dermatitis. These may be primary age-related changes in epidermal immune function or may be secondary to aging of the organism. In either case, the age-related changes in epidermal immunity may contribute to the increased susceptibility to cutaneous infections and neoplasms with advancing age.

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Aging Animals Antibody Formation Humans Immunity, Cellular Langerhans Cells Lymphokines Skin Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.Review

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D N Sauder. 1989. Effect of age on epidermal immune function.. https://pubmed.ncbi.nlm.nih.gov/2645993/

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