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[The climacteric--physiology or pathology?].

W Distler
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Abstract

Nearly 30 years of a woman's life is spent after cessation of the reproductive function and about 30% of the female population in Europe is postmenopausal. The medical infirmities resulting from estrogen deprivation among postmenopausal women take a high toll. The greatest number of hip fractures because of osteoporosis occur in this group, resulting in a high death (20%-30%) and morbidity rate. Estrogen deprivation leads to a change of the lipid metabolism with acceleration of arteriosclerosis. While the "estrogen forever" era closed with a striking rise in the incidence of adenocarcinoma of the endometrium, combined estrogen-gestagen treatment drastically decreases the incidence of endometrial and breast carcinoma. Therefore, physicians must be aware of the benefits of estrogen-gestagen treatment and act appropriately.

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ClimactericEstrogensFemaleHumansLipidsMiddle AgedOsteoporosis, PostmenopausalRisk FactorsEnglish AbstractJournal ArticleReview

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BibTeXRIS

W Distler. 1989. [The climacteric--physiology or pathology?].. https://doi.org/10.1007/bf02417633

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