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Atypical scleroderma associated with multiple myeloma.

H Nakanishi·K Takehara·Y Soma·Y Ishibashi
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Abstract

A case of atypical scleroderma associated with multiple myeloma is reported. The patient was a 50-year-old male; morphea-like plaques with brownish pigmentation were scattered on the whole body and sclerodactylia-like changes, contracture of fingers and polymyositis were observed. Histological findings in the sclerotic lesions were consistent with scleroderma. One year later, M-protein (IgG, kappa-chain) appeared in the serum and 3 years from the onset, the patient was diagnosed as multiple myeloma by bone marrow examination. It is speculated that abnormal immunological reactions related to multiple myeloma caused scleroderma-like lesions.

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CollagenHumansMaleMiddle AgedMultiple MyelomaPigmentation DisordersScleroderma, LocalizedSkinCase ReportsJournal Article

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H Nakanishi, K Takehara, Y Soma, Y Ishibashi. 1989. Atypical scleroderma associated with multiple myeloma.. https://doi.org/10.1159/000248420

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