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PubMed · 284355

Genetic translocation in Staphylococcus aureus.

R P Novick·I Edelman·M D Schwesinger·A D Gruss·E C Swanson·P A Pattee
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Abstract

A 5.2-kilobase pair transposon, Tn551, has been found in Staphylococcus aureus, a Gram-positive bacterium. Initially detected on plasmid pI258, it undergoes rec-independent transposition to multiple chromosomal and plasmid sites, sometimes causing insertional inactivation. Unlike most other transposons, Tn551 undergoes apparently precise excision as a rule. The initial observation of Tn551 transition involved UV inactivation of the carrier plasmid; this would appear to be a general means of detecting transposable elements.

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Chromosome DeletionChromosome MappingDrug Resistance, MicrobialErythromycinGenesPlasmidsR FactorsRecombination, GeneticStaphylococcus aureusTranslocation, GeneticJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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R P Novick, I Edelman, M D Schwesinger, A D Gruss, E C Swanson, P A Pattee. 1979. Genetic translocation in Staphylococcus aureus.. https://doi.org/10.1073/pnas.76.1.400

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