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Phosgene: a practitioner's viewpoint.

B A Wells
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Abstract

Clinical experience with five patients exposed to phosgene is described. The treatment of phosgene poisoning was focused upon the presenting problem, pulmonary edema. Arterial hypoxemia was treated with a face mask with 10 cm CPAP with the FiO2 adjusted as needed or with a volume ventilator with controlled ventilation. Ventilation was controlled to reduce the work of breathing. Metabolic acidosis was treated with NaCHO3 to produce a normal pH. A vigorous program of diuresis was used to treat the pulmonary edema. Lasix was administered to produce a negative fluid balance while maintaining a good urinary output. The negative fluid balance correlated well with reduced oxygen requirements.

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Acid-Base ImbalanceAdultBicarbonatesCombined Modality TherapyFurosemideHumansHypoxiaLaryngeal EdemaMaleOccupational DiseasesOxygen Inhalation TherapyPhosgenePulmonary EdemaSodiumSodium BicarbonateCase ReportsJournal Article

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B A Wells. 1985. Phosgene: a practitioner's viewpoint.. https://doi.org/10.1177/074823378500100209

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