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PubMed · 3080930

Factor VIII complex in canine plasma after submaximal treadmill exercise.

M A Turrentine·A W Hahn·G S Johnson
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Abstract

Exercise-induced changes in the plasma concentrations of coagulation factor VIII and von Willebrand factor were evaluated, using 8 random-source adult dogs that exercised on a treadmill for 5 to 10 minutes (mean running time = 8.3 minutes). Maximum treadmill speeds attained by the dogs were 11 to 18 km/hr, and the mean of the maximum individual speeds was 14.3 km/hr. Maximum heart rates of individual dogs during exercise were 190 to 250 beats/min with a mean of 218 beats/min (a 2.4-fold increase over the mean preexercise rate). Exercise did not induce significant increases in plasma concentrations of factor VIII coagulant activity, coagglutinin co-factor activity, or factor VIII-related antigen. Results indicated that submaximal exercise does not induce increases in plasma concentrations of coagulation factor VIII or von Willebrand factor in the dog.

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AnimalsAntigensCollectinsDogsFactor VIIIMalePhysical ExertionSerum Globulinsvon Willebrand FactorJournal ArticleResearch Support, Non-U.S. Gov't

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M A Turrentine, A W Hahn, G S Johnson. 1986. Factor VIII complex in canine plasma after submaximal treadmill exercise.. https://pubmed.ncbi.nlm.nih.gov/3080930/

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