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PubMed · 3100477

T-lymphocyte subsets modifications in multiple sclerosis: correlation with clinical disease activity.

M Prencipe·E Salerni·C D'Aurizio·C Marini·D Adorno·A M Berghella·P Pellegrini·F Papola·C U Casciani
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Abstract

Serial analyses of peripheral blood T-lymphocyte subsets were performed in 280 samples collected over a 27 months period from 14 multiple sclerosis patients. A significant decrease of T8+ cells was found in 47.1% (47/87) of blood samples collected within four weeks of onset of a relapse opposed to 2.1% (1/47) of samples collected during the four weeks before a relapse and to 3.4% (5/146) of those collected over four weeks after a relapse. Changes of T-cells subsets appear to correlate with disease activity, but normal findings observed before relapses suggest that the decrease of T8+ cells cannot be used as valid predictor of relapse.

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Antigens, Differentiation, T-LymphocyteAntigens, SurfaceFemaleHumansMaleMultiple SclerosisT-LymphocytesJournal Article

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M Prencipe, E Salerni, C D'Aurizio, C Marini, D Adorno, A M Berghella, P Pellegrini, F Papola, C U Casciani. 1986. T-lymphocyte subsets modifications in multiple sclerosis: correlation with clinical disease activity.. https://doi.org/10.1007/bf02341471

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