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Vitamin D2 in vertebrate evolution.

A W Hay·G Watson
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Abstract

1. The affinities of the specific vitamin D plasma transport proteins for 25-hydroxyergocalciferol and 25-hydroxycholecalciferol were studied in sixty three vertebrate species. 2. Fish, reptile, bird and monotreme plasma proteins bound 25-hydroxyergocalciferol considerably less efficiently than 25-hydroxycholecalciferol. 3. Vitamin D transport proteins from twenty-two placental mammals bound 25-hydroxyergocalciferol and 25-hydroxycholecalciferol with equal efficiency. 4. Proteins from nine mammals bound 25-hydroxycholecalciferol 10-30% more efficiently than 25-hydroxyergocalciferol.

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AnimalsBiological EvolutionErgocalciferolsVertebratesJournal ArticleResearch Support, Non-U.S. Gov't

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A W Hay, G Watson. 1977. Vitamin D2 in vertebrate evolution.. https://doi.org/10.1016/0305-0491(77)90234-6

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