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Generalized epilepsy in childhood: some notes from a developmental perspective.

M De Negri
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Abstract

Efforts to establish more detailed classification of childhood epilepsy have increased our knowledge in this field, but have also led to a tendency of excessive subdivision, especially in generalized forms. This paper emphasizes the need for the reconsideration of a number of basic factors that favour a more unitary physiopathogenetic and clinical interpretation: 1) the electroclinical pattern is age-related; 2) the electroclinical paroxysmal expressiveness is greatest in childhood; 3) two types of manifestations can be distinguished in the process of spread and generalization (a benzodiazepine-sensitive complex associated with a more regular and organized EEG pattern, and a corticotropin-sensitive complex associated with an irregular, unorganized EEG pattern).

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BrainChildChild, PreschoolElectroencephalographyEpilepsyHumansInfantJournal Article

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M De Negri. 1988. Generalized epilepsy in childhood: some notes from a developmental perspective.. https://doi.org/10.1016/s0387-7604(88)80057-3

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