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PubMed · 325492

Vitamin E and neonatal hemolysis.

S J Gross·S A Landaw·F A Oski
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Abstract

A study was designed to determine if the presence of vitamin E deficiency during the first week of life played a contributory role in the shortened red cell life span observed in the premature infant. Carboxyhemoglobin values were used as an index of hemolysis. Ten infants received vitamin E administered intramuscularly in a total dose of 125 mg/kg during days 3 to 7 of life; ten infants served as controls. The mean percent carboxyhemoglobin level fell significantly from day 3 to day 8 in the treated group (1.08% to 0.78%) whereas the mean value remained unchanged at 0.96% in the control group. The administration of vitamin E appears to reduce but not eliminate the accelerated red cell destruction that characterizes the preterm infant. Pediatrics, 59:995-997, 1677, VITAMIN E, HEMOLYSIS, PREMATURE INFANT, CARBOXYHEMOGLOBIN.

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Apgar ScoreCarboxyhemoglobinClinical Trials as TopicDrug EvaluationErythroblastosis, FetalErythrocyte AgingFemaleHemolysisHumansInfant, NewbornPregnancyVitamin EClinical TrialJournal Article

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S J Gross, S A Landaw, F A Oski. 1977. Vitamin E and neonatal hemolysis.. https://pubmed.ncbi.nlm.nih.gov/325492/

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