Etonitazene as a reinforcer: oral intake of etonitazene by rhesus monkeys.

M E Carroll; R A Meisch

doi:10.1007/bf00426626

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Etonitazene as a reinforcer: oral intake of etonitazene by rhesus monkeys.

M E Carroll·R A Meisch

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Abstract

Drinking of etonitazene HCI was studied in three rhesus monkeys during daily 3-h sessions. As the drug concentration was increased, the number of liquid deliveries decreased, and etonitazene intake (microgram/kg body weight) increased. As fixed-ratio (FR) requirements were increased, rate of responding increased, and liquid deliveries slightly decreased. When water was substituted for the drug, there was a large increase in responding for several sessions, followed by a slow decline to low rates. When etonitazene was reintroduced, responding abruptly increased to previous drug levels. These data suggest that etonitazene can serve as a positive reinforcer when taken orally by rhesus monkeys.

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Animals Benzimidazoles Drinking Behavior Food Food Deprivation Haplorhini Macaca mulatta Male Reinforcement, Psychology Journal Article Research Support, U.S. Gov't, P.H.S.

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M E Carroll, R A Meisch. 1978-12-08. Etonitazene as a reinforcer: oral intake of etonitazene by rhesus monkeys.. https://doi.org/10.1007/bf00426626

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