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The pyrazine-binding protein and olfaction.

E Bignetti·P Cattaneo·A Cavaggioni·G Damiani·R Tirindelli
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Abstract

1. The present results provide circumstantial evidence, but not a proof, that the Pyrazine-binding Protein is an odorant carrier molecule of fundamental importance. 2. At first sight a role for a secretory protein in olfaction is not obvious. 3. Odorants freely diffuse in air, in water and in lipids, and the use of carrier proteins, would seem superfluous unless a very special combination with the odorant occurs [Gaupp E. (1902) In Anatomie des Frosches, 2nd Edn, pp. 673. Vieweg-Verlag, Braunschweig]. 4. The possibility should be considered that the Pyrazine-binding Protein and the urinary proteins belong to a large family of species-specific secretory molecules which, with the odorant bound, directly stimulate the receptor cell.

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AnimalsCarrier ProteinsPyrazinesReceptors, OdorantSensory Receptor CellsSmellSpecies SpecificityComparative StudyJournal ArticleReview

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E Bignetti, P Cattaneo, A Cavaggioni, G Damiani, R Tirindelli. 1988. The pyrazine-binding protein and olfaction.. https://doi.org/10.1016/0305-0491(88)90029-6

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