Flow and function in machine-preserved kidneys.

D Sampson; H M Jun; P Walczak

doi:10.1002/bjs.1800650111

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Flow and function in machine-preserved kidneys.

D Sampson·H M Jun·P Walczak

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Abstract

One hundred machine-preserved cadaver kidneys were transplanted irrespective of their flow rates on the preservation machine. Twenty-five per cent had flows of below 100 ml/min and 11 per cent had flows of below 80 ml/min. There was no correlation between the flow rate and function at 1, 3 or 12 months. There was no difference in the flow rate between those kidneys which functioned immediately and those which never functioned. A fall in flow rate was associated with acute tubular necrosis of longer duration but eventual function was not impaired. There was a higher incidence of early aggressive rejection in kidneys which functioned immediately. Preservation failure per se is a rare cause of primary non-function. Adherence to a policy of ignoring the flow characteristics of machine-preserved kidneys could make up to 25 per cent more kidneys available for transplantation.

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Cadaver Graft Rejection Humans Kidney Kidney Transplantation Kidney Tubular Necrosis, Acute Organ Preservation Perfusion Tissue Preservation Transplantation, Homologous Urodynamics Journal Article

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D Sampson, H M Jun, P Walczak. 1978. Flow and function in machine-preserved kidneys.. https://doi.org/10.1002/bjs.1800650111

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