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PubMed · 3433972

CSF production rate: "real time" estimation.

R A Minns·J K Brown·H M Engleman
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Abstract

CSF production rate has been measured by a drip detector method in 5 cases of childhood hydrocephalus undergoing closed ventricular drainage. The rate of production of CSF with this "real time" estimation is shown not to be constant but to be discontinuous and may vary by a factor of 10 over a one hour period, although the average rate of CSF production remains within previously established normal limits.

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Cerebrospinal FluidChildChild, PreschoolChoroid PlexusFemaleHumansHydrocephalusInfantMalePulsatile FlowTime FactorsCase ReportsJournal ArticleResearch Support, Non-U.S. Gov't

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R A Minns, J K Brown, H M Engleman. 1987. CSF production rate: "real time" estimation.. https://pubmed.ncbi.nlm.nih.gov/3433972/

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Cerebrospinal fluid dissecting into spinal epidural space after lumbar puncture causing cauda equina syndrome: review of literature and illustrative case.

OBJECTS: We report a case of epidural cerebrospinal fluid (CSF) leak after lumbar puncture caused by CSF dissecting into the spinal epidural space. The incidence of this phenomenon may be higher than suspected, although most cases may remain asymptomatic. MATERIALS AND METHODS: A 4-year-old girl with new-onset seizure underwent a diagnostic lumbar puncture, the results of which were normal; 3 h later, she began experiencing severe low-pressure headaches and lower back pain, bilateral lower extremity weakness, numbness, and pain, and urinary retention when upright. Spinal MRI demonstrated extensive epidural CSF collection posterior to the thecal sac extending from the cervicothoracic junction to the sacrum. After 48 h in the supine position and gradual mobilization, the patient had complete resolution of symptoms and no neurological sequelae. CONCLUSION: Patients usually recover without any neurological deficits after conservative treatment. Prone or lateral decubitus positioning immediately after lumbar puncture may decrease the incidence of this phenomenon.

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