[IgA nephropathy].

Abstract

Among the chronic glomerulonephritides the IgA-nephropathy is one of the most frequent forms. On account of the possibility of the transition into the terminal renal insufficiency new ways for the therapeutic influence on this disease must be found. In the hitherto used therapy methods above all corticosteroids, cytostatic drugs, inhibitors of thrombocyte aggregation and antiphlogistic drugs were applied. According to the recent investigations from the application of eicosapentaenic acid and the use of plasmapheresis possibilities result to favourably influence the course of the disease and thus to prevent a progression of this disease. By the administration of diphenylhydantoin the IgA-level could, indeed, be lowered, but an influence on the course of the disease could not be proved.