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[HLA and thyroid cancer].

H Dralle·M Robin-Winn·L Reilmann·A Laue·M Török
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Abstract

HLA typing was performed in 51 patients to analyse the pathogenetic background of differentiated and medullary thyroid carcinomas. A higher incidence of Bw62 and DR5 was observed in patients with papillary carcinoma (n = 24), DRw6 antigen in follicular carcinoma (n = 13), and DR3 antigen in patients with medullary carcinoma (n = 11). The DR3 antigen was present in one of two patients with a familial history of medullary thyroid carcinoma. Therefore, HLA typing is not suitable as a screening method for the detection of early thyroid carcinoma.

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AdenocarcinomaCarcinomaCarcinoma, PapillaryChromosome MappingGene FrequencyHLA AntigensHLA-A AntigensHLA-B AntigensHLA-C AntigensHLA-DR AntigensHistocompatibility Antigens Class IIHumansThyroid NeoplasmsEnglish AbstractJournal ArticleResearch Support, Non-U.S. Gov't

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H Dralle, M Robin-Winn, L Reilmann, A Laue, M Török. 1986-06-02. [HLA and thyroid cancer].. https://doi.org/10.1007/bf01713060

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