Elastase activity in capillary and aortic endothelial cells.

D C West; S Kumar

PubMed · 3643012

Elastase activity in capillary and aortic endothelial cells.

Abstract

Tissue cultured bovine capillary and aortic endothelial cells were examined for cellular and secreted proteinase activity. Cell-lysates from both sources showed significant elastase activity but differed in the level of activity and the pH-optimum and inhibition profile. Secretion of elastase was only detected using aortic cells. Tumour angiogenesis factor (TAF), heparin or 12-0-tetradecanoyl-phorbol-acetate (TPA) had no effect on the levels of cell-associated or secreted elastase.

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Angiogenesis Inducing Agents Animals Aorta Capillaries Cattle Culture Techniques Endothelium Hydrogen-Ion Concentration Mice Pancreatic Elastase Substrate Specificity Tetradecanoylphorbol Acetate Journal Article

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D C West, S Kumar. Elastase activity in capillary and aortic endothelial cells.. https://pubmed.ncbi.nlm.nih.gov/3643012/

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