[Computer programs for the analysis of nucleotide sequences (MALK)].

A A Mironov; N N Aleksandrov; L V Liunovskaia-Gurova; A E Kister

PubMed · 3657768

[Computer programs for the analysis of nucleotide sequences (MALK)].

A A Mironov·N N Aleksandrov·L V Liunovskaia-Gurova·A E Kister

Abstract

A system for the computer analysis of nucleic acid and protein sequences ("Helix") is described. Format of the DNA sequences is EMBL--compatible and may be easily commented with the help of convenient menus. "Helix" has also following possibilities: an effective alignment of gele reading data and formation of the final sequence; simple making of recombined molecules "in calcular"; calculations of nucleotide and dinucleotide distribution along the sequence; looking for coding frames; calculations percentage of codons and amino acids in coding frames; searching for direct and inverted repeats; sequences alignment; protein secondary structure prediction; restriction mapping; DNA--protein translation. "Helix" also contain programs for RNA-structure prediction, looking for homologies throughover the EMAL bank, choosing optimal sequence for probes and searching promoters. All the programs are written at FORTRAN-77 and automatically translated into FORTRAN-4. "Helix" require only 64 kbite.

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A A Mironov, N N Aleksandrov, L V Liunovskaia-Gurova, A E Kister. [Computer programs for the analysis of nucleotide sequences (MALK)].. https://pubmed.ncbi.nlm.nih.gov/3657768/

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