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PubMed · 3760006

Antithrombogenic heparinized polyacrylonitrile copolymer.

H Miyama·N Fujii·A Kuwano·S Nagaoka·Y Mori·Y Noishiki
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Abstract

A new antithrombogenic polymer was synthesized by the photograft-copolymerization of methoxypolyethyleneglycol methacrylate and dimethylaminoethyl methacrylate to polyacrylonitrile containing bromine atoms, and by quaternizing and heparinizing the graft-copolymer. Hydrophilicity and heparin content of the polymer could be controlled by changing the feed ratio of the acrylates to be grafted. The heparinized polymer showed excellent mechanical and antithrombogenic properties.

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Acrylic ResinsAnimalsBiocompatible MaterialsDogsHeparinStress, MechanicalSuturesTensile StrengthThrombosisJournal ArticleResearch Support, Non-U.S. Gov't

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H Miyama, N Fujii, A Kuwano, S Nagaoka, Y Mori, Y Noishiki. 1986. Antithrombogenic heparinized polyacrylonitrile copolymer.. https://doi.org/10.1002/jbm.820200705

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