Screening workers exposed to suspect bladder carcinogens.

Abstract

In England, screening programs for detecting workers at increased risk for bladder cancer have helped identify the following issues: Early treatment should be considered part of the "screen." The early natural history of the disease is of some importance in conceptualizing the problems and results of screening. The epidemiology of high-risk groups might prove invaluable in extending screening to other groups. Of particular use might be aspects of genetic susceptibility. To address these points, an observational study has begun in Huddersfield to set up a trial of very early disease, contrasting therapy for early lesions with the long-term aim of altering the occurrence of invasive bladder lesions in the group of interest.