Relapse in recurrent unipolar depression.

D J Kupfer; E Frank

doi:10.1176/ajp.144.1.86

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PubMed · 3799845

Relapse in recurrent unipolar depression.

D J Kupfer·E Frank

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Abstract

Treatment of the acute phase of recurrent depression has become both routine and successful in the last decade, but the rates of relapse and recurrence remain a problem. In this study a combined psychopharmacologic/psychotherapeutic approach to the acute and continuation treatment of unipolar depressed patients was used. For 59 patients who completed the continuation phase of treatment, the relapse rate after 8 weeks of recovery was 8.5%. Since other recent studies of recurrent depression have reported relapse rates of 15%-22%, these results suggest that there are advantages in combined treatment.

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Acute Disease Adult Combined Modality Therapy Depressive Disorder Female Humans Imipramine Male Patient Dropouts Psychiatric Status Rating Scales Psychotherapy Recurrence Time Factors Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

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D J Kupfer, E Frank. 1987. Relapse in recurrent unipolar depression.. https://doi.org/10.1176/ajp.144.1.86

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