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PubMed · 3800682

[Morphologic changes in the adrenal cortex in Itsenko-Cushing's syndrome].

S A Kalashnikov·B G Lisochkin
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Abstract

Having studied the results of investigation of 132 patients with Icenko-Cushing syndrome (68 out of them with different structural variants of adrenal tumours, 68--without adrenal tumours), the authors came to the conclusion that adenomas of dark and mixed polymorphic cells belong to hormonally active adrenal tumours, while light-cell monomorphic adenomas belong to hormonally inactive tumours. An electron-microscopic study provides identification of signs of functional activity in adenomas and cancer tumours, to clear up the additional criteria of anaplasia in them. In patients with Icenko-Cushing syndrome, but without a tumour in the adrenal cortex ultrastructural changes in corticocytes are characteristic of the increase of cellular proliferation and the decrease of incretory activity. The follow-up results of surgical treatment were studied in all cases.

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AdenomaAdrenal CortexAdrenal Cortex NeoplasmsCushing SyndromeHumansHyperplasiaMicroscopy, ElectronEnglish AbstractJournal Article

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S A Kalashnikov, B G Lisochkin. 1986. [Morphologic changes in the adrenal cortex in Itsenko-Cushing's syndrome].. https://pubmed.ncbi.nlm.nih.gov/3800682/

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