PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 3838501

A BASIC computer program for use in evaluating enzyme-substrate-inhibitor kinetics.

R A Lutz·D Rodbard
View original source ↗Export metadata ↓

Abstract

The source did not provide an abstract. Follow the original record for more information.

Explore related subjects

ComputersEnzyme InhibitorsEnzymesKineticsSoftwareLetter

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

R A Lutz, D Rodbard. 1985. A BASIC computer program for use in evaluating enzyme-substrate-inhibitor kinetics.. https://pubmed.ncbi.nlm.nih.gov/3838501/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed1992

Molecular orbital study on the glutathione-dependent detoxication of ozonides.

The present paper describes a theoretical study on the mechanism underlying the reaction of cellular glutathione (GSH) with polyunsaturated fatty acid ozonides. The reaction can be catalyzed by glutathione S-transferases and leads to detoxication of the ozonides. Semi-empirical molecular orbital computer calculations suggest that the reaction of glutathione with ozonides involves a nucleophilic attack at one of the carbon atoms of the ozonide ring, instead of at one of the peroxidic oxygen atoms of the ozonide ring. This implies a mechanism different from that of the glutathione S-transferase-mediated reaction with hydroperoxides, previously proposed for the glutathione-dependent detoxication of fatty acid ozonides.

Computers↗