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PubMed · 3853968

Estimating viral concentrations: a reliable computation method programmed on a pocket calculator.

J Husson-van Vliet·P Roussel
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Abstract

A method has been developed, based on the Newton-Raphson iterative procedure, for calculating the concentration of viral suspensions from the dose-response data yielded by the cytopathic effect assays. The computation method provides the maximum likelihood estimate with its 95% approximated confidence limits, and determines the value of chi 2 for testing the goodness of the fit. A program for a Hewlett-Packard 41C calculator is presented which is suitable to most experimental situations.

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ComputersCytopathogenic Effect, ViralModels, BiologicalSoftwareVirusesJournal Article

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BibTeXRIS

J Husson-van Vliet, P Roussel. 1985. Estimating viral concentrations: a reliable computation method programmed on a pocket calculator.. https://doi.org/10.1016/0169-2607(85)90001-x

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