Antioxidant effects on cell-mediated immunity.

H C Meeker; M L Eskew; W Scheuchenzuber; R W Scholz; A Zarkower

doi:10.1002/jlb.38.4.451

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Antioxidant effects on cell-mediated immunity.

H C Meeker·M L Eskew·W Scheuchenzuber·R W Scholz·A Zarkower

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Abstract

Experiments were performed to determine the effects of dietary selenium and/or vitamin E deficiency on cell-mediated cytotoxicity in the mouse. Natural killer cell-mediated cytotoxicity (NKCC) was depressed after 8 wk on diets deficient in selenium and/or vitamin E. In contrast, antibody-dependent cell-mediated cytotoxicity (ADCC) was not affected by 8 wk of dietary deficiency of selenium and/or vitamin E. T-lymphocyte-mediated cytotoxicity (TCMC) was found to be depressed by combined selenium-vitamin E deficiency after 7 weeks on diets.

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Animals Antibody-Dependent Cell Cytotoxicity Cytotoxicity, Immunologic Female Glutathione Peroxidase Immunity, Cellular Immunity, Innate Killer Cells, Natural Mice Mice, Inbred BALB C Selenium T-Lymphocytes, Cytotoxic Vitamin E Deficiency Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

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H C Meeker, M L Eskew, W Scheuchenzuber, R W Scholz, A Zarkower. 1985. Antioxidant effects on cell-mediated immunity.. https://doi.org/10.1002/jlb.38.4.451

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