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PubMed · 3925823

Delayed-type hypersensitivity responses induced by bovine colostral components.

J K Radosevich·G H Scott·G B Olson
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Abstract

Transfer factor-type substances obtained from leukocytic cells and fluid portions of bovine colostrum caused effective passive transfer of delayed-type hypersensitivity responses across species barriers. Passive transfer of Brucella abortus sensitivity was obtained with equal regularity when using components derived from peripheral blood and colostrum of dams sensitized at 3 and 9 months of age. Colostral feedings to calves caused the passive transfer of delayed-type hypersensitivity as early as 2 days after parturition. The findings indicated that colostral components were important in the process of cell-mediated immunity.

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AnimalsBrucella abortusCattleCattle DiseasesColostrumGuinea PigsHypersensitivity, DelayedImmunization, PassiveRodent DiseasesSkin TestsJournal Article

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J K Radosevich, G H Scott, G B Olson. 1985. Delayed-type hypersensitivity responses induced by bovine colostral components.. https://pubmed.ncbi.nlm.nih.gov/3925823/

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