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PubMed · 3927927

[Toxicologic studies with thymostimulin].

F Leuschner·W Neumann
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Abstract

Thymostimulin (Tp-1 Serono) was tested toxicological in rats and monkeys during 6 weeks of repeated administration. Corresponding to the therapeutic use intended in man the substance was given to rats and monkeys intramuscularly in dosages of 10 or 100 mg/kg b.w. and due to technical reasons subcutaneously in a dosage of 1000 mg/kg b.w. No substance-related effects, either systemic or local, were observed in the monkeys. After treatment with the high dose level (1000 mg/kg b.w. s.c.) the rats exhibited inflammatory changes in the region of the injection sites.

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AnimalsFemaleHaplorhiniMaleRatsRats, Inbred StrainsThymus ExtractsEnglish AbstractJournal Article

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F Leuschner, W Neumann. 1985. [Toxicologic studies with thymostimulin].. https://pubmed.ncbi.nlm.nih.gov/3927927/

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