Selenium and vitamin E stability in parenteral solutions.

C D McGee; M G Mascarenhas; M J Ostro; G Tsallas; K N Jeejeebhoy

doi:10.1177/0148607185009005568

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Selenium and vitamin E stability in parenteral solutions.

C D McGee·M G Mascarenhas·M J Ostro·G Tsallas·K N Jeejeebhoy

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Abstract

Stability of alpha-tocopherol acetate and selenium in amino acid/dextrose solutions with SoluZyme or MVI-1000 vitamin injections was evaluated following exposure to fluorescent lighting and room temperature, and after flowing through an infusion apparatus. The stability of selenium in parenteral solutions for a 10-wk period was also determined. In each condition no significant loss of alpha-tocopherol acetate or selenium was observed. It was concluded that alpha-tocopherol acetate and selenium as selenious acid are stable in parenteral solutions and no significant loss occurs during delivery to patients.

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Drug Stability Drug Storage Infusions, Parenteral Lighting Parenteral Nutrition, Total Selenium Temperature Vitamin E Comparative Study Journal Article Research Support, Non-U.S. Gov't

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C D McGee, M G Mascarenhas, M J Ostro, G Tsallas, K N Jeejeebhoy. Selenium and vitamin E stability in parenteral solutions.. https://doi.org/10.1177/0148607185009005568

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