Hypercholesterolaemia accentuates platelet activity.

I F Lane; K R Poskitt; J T Irwin; C N McCollum

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PubMed · 3944521

Hypercholesterolaemia accentuates platelet activity.

I F Lane·K R Poskitt·J T Irwin·C N McCollum

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Abstract

Platelet aggregation response to collagen has been studied in 20 rabbits, randomly allocated to receive a normal (control) or high cholesterol diet. The sensitivity of platelets to collagen was significantly higher in the hypercholesterolaemic group (p less than 0.01) compared to controls. All hypercholesterolaemic rabbits developed generalised atherosclerosis and this may be due to increased circulating platelet activity.

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Animals Arteriosclerosis Cholesterol, Dietary Collagen Hypercholesterolemia In Vitro Techniques Male Platelet Aggregation Rabbits Triglycerides Journal Article

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I F Lane, K R Poskitt, J T Irwin, C N McCollum. 1986. Hypercholesterolaemia accentuates platelet activity.. https://pubmed.ncbi.nlm.nih.gov/3944521/

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