Functional pattern of sacral root stimulation: III. Erection.

J W Thüroff; M A Bazeed; R A Schmidt; E A Tanagho

doi:10.1159/000472598

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Functional pattern of sacral root stimulation: III. Erection.

J W Thüroff·M A Bazeed·R A Schmidt·E A Tanagho

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Abstract

The mechanism of canine penile erection was studied in 6 'chronic' and 15 'acute' male dogs by means of sacral root stimulation combined with pharmacologic studies. The basic mechanism of erection cannot be explained by a pure increase in arterial perfusion of the cavernous spaces due to neural vasomotor regulation. The vasomotor mechanism, whether pure arteriolar vasodilation, or venous drainage impairment, or secondary to as yet undefined behavior of the corporal smooth muscle, can be activated by stimulation of the parasympathetic outflow. Those preganglionic fibers may synapse to noncholinergic and non-beta-adrenergic neurons, which release a yet unidentified vasodilator neurotransmitter mediating the neurovascular effect.

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Animals Blood Pressure Depression, Chemical Dogs Electric Stimulation Epinephrine Isoproterenol Male Penile Erection Phentolamine Propantheline Sacrococcygeal Region Spinal Nerve Roots Terbutaline Trimethaphan Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

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J W Thüroff, M A Bazeed, R A Schmidt, E A Tanagho. 1986. Functional pattern of sacral root stimulation: III. Erection.. https://doi.org/10.1159/000472598

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