PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 397865

[Postoperative hypergastrinemia].

M Zanghì·V Morici·S Sequenzia·S Grillo
View original source ↗Export metadata ↓

Abstract

After reviewing the more recent acquisitions on the physiology and pathophysiology of gastrin, the authors concentrate on situations of hypergastrinemia, which they divide into a hyperhydrochloric and a hypohydrochloric variety. Among the former, which they subdivide into preoperative and postoperative, the authors discuss problems of differential diagnosis versus peptic ulcers in patients so afflicted. To that end they propose diagnostic policies comprising among other instrumental and laboratory tests the study of gastric secretion, blood gastrin levels in basal conditions and after stimulation by a protein meal, BBS, secretin, and calcium. From analysis of the results of such tests they were able to find a precise nosographic placement for postoperative hypergastrinemia, and from there they arrived at surgical programs aiming to correct postoperative peptic ulcers on the basis of their etiology and pathogenesis.

Explore related subjects

GastrectomyGastrinsHumansHyperparathyroidismPeptic UlcerPostoperative ComplicationsPyloric StenosisStomach DiseasesVagotomyZollinger-Ellison SyndromeJournal ArticleReview

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

M Zanghì, V Morici, S Sequenzia, S Grillo. 1979. [Postoperative hypergastrinemia].. https://pubmed.ncbi.nlm.nih.gov/397865/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2007

[The advances of laparoscopic treatment for gastric cancer].

Recently, laparoscopic surgery for gastric cancer is very interesting topic in the treatment of gastric cancer. Therefore,many surgeons are attempting laparoscopic surgery. However, the technique of this surgery has never been established yet. From July 1997 to July 2006, we performed laparoscopic surgeries for 420 cases of gastric cancer with lymph node dissection. We have describe our technical advances in laparoscopic treatment for gastric cancer along with the clinical outcomes.

Gastrectomy↗
PubMed2006

Meta-analysis of short-term outcomes after laparoscopy-assisted distal gastrectomy.

AIM: To elucidate the current status of laparoscopy-assisted distal gastrectomy (LADG) with regard to its short-term outcomes by comparing it with conventional open distal gastrectomy (CODG). METHODS: Original articles published from January 1991 to August 2006 were searched in the MEDLINE, EMBASE, and Cochrane Controlled Trials Register. Clinical appraisal and data extraction were conducted independently by 2 reviewers. A meta-analysis was performed using a random effects model. RESULTS: Outcomes of 1611 procedures from 4 randomized controlled trials and 12 retrospective studies were analyzed. Compared to CODG, LADG was a longer procedure (weighted mean difference [WMD] 54.3; 95% confidence interval [CI] 38.8 to 69.8; P < 0.001), but was associated with a lower associated morbidity (odds ratio [OR] 0.54; 95% CI 0.37 to 0.77; P < 0.001); this was most significant for postoperative ileus (OR 0.27; 95% CI 0.09 to 0.84; P = 0.02). There was no significant difference between the two groups in anastomotic, pulmonary, and wound complications and mortality. Duration from surgery to first passage of flatus was faster (WMD -0.68; 95% CI -0.85 to -0.50; P < 0.001) and the frequency of additional analgesic requirement (WMD -1.36; 95% CI -2.44 to -0.28; P = 0.01), and duration of hospital stay (WMD -5.51; 95% CI -7.61 to -3.42; P < 0.001) were significantly lower after LADG. However, a significantly higher number of lymph nodes were dissected by CODG (WMD -4.35; 95% CI -5.73 to -2.98; P < 0.001). CONCLUSION: LADG for early gastric cancer is associated with a lower morbidity, less pain, faster bowel function recovery, and shorter hospital stay.

Gastrectomy↗