Relationship between pulmonary function and sleep-induced respiratory abnormalities.

E Onal; J A Leech; M Lopata

doi:10.1378/chest.87.4.437

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Relationship between pulmonary function and sleep-induced respiratory abnormalities.

E Onal·J A Leech·M Lopata

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Abstract

The relationships between pulmonary function and sleep-induced respiratory events were studied in 34 consecutive male patients with suspected sleep apnea syndrome. In view of the effects of obstructive airway disease on pulmonary volume and airway resistance (Raw), patients were divided into two groups, those with and those without obstructive airway disease. Percent predicted functional residual capacity (FRC) correlated significantly with the apnea-plus-hypopnea index (AHI) in patients with and without obstructive airway disease (r = -0.62 and p less than 0.01; and r = -0.57 and p less than 0.01, respectively) whereas percent predicted total lung capacity had a significant relationship with AHI only in patients with obstructive airway disease (r = -0.80; p less than 0.001). In patients without such disease, a significant correlation between inspiratory airway conductance (Gaw) and AHI (r = -0.47; p less than 0.05) was also present, while percent predicted FRC and Gaw did not correlate with normalized weight. These findings suggest that decreased pulmonary volume and increased Raw contribute to the severity of sleep-induced respiratory abnormalities in patients with sleep apnea syndrome regardless of the degree of obesity.

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Adolescent Adult Aged Airway Resistance Blood Gas Analysis Body Weight Forced Expiratory Volume Humans Male Middle Aged Pulmonary Ventilation Residual Volume Respiration Sleep Apnea Syndromes Vital Capacity Journal Article Research Support, U.S. Gov't, Non-P.H.S.

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E Onal, J A Leech, M Lopata. 1985. Relationship between pulmonary function and sleep-induced respiratory abnormalities.. https://doi.org/10.1378/chest.87.4.437

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