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PubMed · 400102

[Technic for studying antitetanus immunity].

P Marconi·F Bistoni·L Tissi·L Mosci·E Cenci·M Pitzurra·F Lusian
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Abstract

The Authors carried out a research work on problems relating to technical aspects to the tetanus immunity tests. Some interesting conclusions have been reached: - Purified and diluted tetanus toxin is best preserved at - 20 degrees C, in pH 7.4 physiological salt solution added with 1% peptone. - Vaccination in small laboratory animals must be done injecting adsorbed anatoxin by a microsyringe, in order to avoid dilution of the original compound. - Protection test using low, i.v. toxin doses is more reliable than serological tests in assessing the acquired resistance level in immuno-prophylaxed animals. - Passive haemagglutination test is much more sensitive when done with turkey instead of sheep red blood cells.

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AnimalsImmunologic TechniquesMaleMiceTetanus ToxinEnglish AbstractJournal Article

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P Marconi, F Bistoni, L Tissi, L Mosci, E Cenci, M Pitzurra, F Lusian. 1979-05-31. [Technic for studying antitetanus immunity].. https://pubmed.ncbi.nlm.nih.gov/400102/

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