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Possible beta-lactamase activities detectable in infective clinical specimens.

G Masuda·S Tomioka
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Abstract

Biological beta-lactam antibiotic-inactivating activities were detected in bacteriuria and suppurating pleural fluids. Clinical specimens were sterilized with membrane filters and the amounts of ampicillin and/or cephalothin which were being inactivated by 1 ml of each filtrate were determined. In general, filtrates which originally yielded Klebsiella sp. tended to show activity against ampicillin; whereas those yielding Enterobacter sp. and Pseudomonas aeruginosa showed activity against cephalothin.

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AmidohydrolasesAmpicillinBacteriuriaCephalosporinaseCephalothinEnterobacteriaceaePenicillinasePleural EffusionPseudomonas aeruginosaStaphylococcus aureusJournal Article

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G Masuda, S Tomioka. 1977. Possible beta-lactamase activities detectable in infective clinical specimens.. https://doi.org/10.7164/antibiotics.30.1093

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