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Murine leukemia viruses: antigenic studies by quantitative complement fixation.

P Gerber·T E O'Connor·S M Birch
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Abstract

The murine leukemia viruses of Rauscher and Friend, derived from plasnma of infected Balb/c mice, was purified. Their antigenic relationship was studied by quantitative complement-fixation reactions with the virion antigen and homologous antiserums. The complement-fixation curves observed in cross-reactions indicated close antigenic similarity between these two leukemia viruses. Highly purified viral preparations contained detectable amounts of host antigens.

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AnimalsAntigensCentrifugationComplement Fixation TestsGuinea PigsIn Vitro TechniquesLeukemia Virus, MurineMiceJournal Article

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P Gerber, T E O'Connor, S M Birch. 1966-05-20. Murine leukemia viruses: antigenic studies by quantitative complement fixation.. https://doi.org/10.1126/science.152.3725.1074

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