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Weight changes with depot neuroleptic maintenance therapy.

D A Johnson·M Breen
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Abstract

A prospective study of schizophrenic patients prescribed injectable depot neuroleptic drugs as maintenance therapy showed a clinically significant weight gain in 55% of patients. No significant difference was shown between flupenthixol decanoate and fluphenazine decanoate, nor was a clinically meaningful relationship shown with dose, or the use of anti-parkinsonian drugs. The weight gain continued for at least 2 years following a mental state relapse. It is suggested that the monitoring of weight and giving of appropriate advice on diet are two essential in maintenance therapy of chronic schizophrenia.

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Body WeightDecanoatesDelayed-Action PreparationsFlupenthixolFluphenazineHumansProspective StudiesSchizophreniaTime FactorsJournal Article

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BibTeXRIS

D A Johnson, M Breen. 1979. Weight changes with depot neuroleptic maintenance therapy.. https://doi.org/10.1111/j.1600-0447.1979.tb00252.x

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