[Coagulation problems associated with massive blood transfusions. An experimental study (author's transl)].

G Witzke; W Abdulla

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PubMed · 484820

[Coagulation problems associated with massive blood transfusions. An experimental study (author's transl)].

G Witzke·W Abdulla

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Abstract

During storage banked blood show changes as far as function and concentration of their corpuscular and plasmatic ingredients are concerned. Antihaemophilic globulin (factor VIII) and pro-accelerin (factor V) in particular lose their activities so quickly that only very few activities still remain after a storage period of 3-5 days. In connection with existing primary diseases but also in trauma and shock a dilution-coagulopathy caused by insufficient supply of factors VIII and V can develop during massive transfusion, and this especially with banked blood already stored over a longer period of time. Therapy of this disturbance of coagulation consists of substituting the missing coagulation factors under heparin protection.

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Blood Coagulation Disorders Blood Coagulation Tests Blood Preservation Blood Transfusion Factor V Factor VIII Humans English Abstract Journal Article

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G Witzke, W Abdulla. 1979. [Coagulation problems associated with massive blood transfusions. An experimental study (author's transl)].. https://pubmed.ncbi.nlm.nih.gov/484820/

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