PubMed · 4890066
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M B Marks. 1969. Stinging insects: allergy implications.. https://doi.org/10.1016/s0031-3955(16)32242-8
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Efficacy of standard IT to reduce medications and symptoms by at least 50% has been demonstrated multiple times. Reports of negative studies of IT deserve only evaluation of why the study design failed to demonstrate efficacy. Emphasis in the US and worldwide should be on education on the appropriate use of allergen IT, improvements in IT therapy, and preparation for the increased demand for allergists-immunologists as Fellowship training programs decline in numbers and individual training slots decrease.
This review starts with a clinical description of the most common unspecific environmental diseases, such as Multiple Chemical Sensitivities (MCS), Idiopathic Environmental Intolerances (IEI) and Sick Building Syndrome (SBS). These syndromes are very controversial discussed between scientific medicine and "clinical ecology". In addition, they have fundamental similarities to Chronic Fatigue Syndrome (CFS) and Fibromyalgia. Finally the spectrum of therapeutic approaches is discussed.
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