PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 52215

Another example of a B variant.

A Simmons·J Twaitt
View original source ↗Export metadata ↓

Abstract

A family in which five members has a weak B variant and one member had a normal A and weak B reaction is reported. It appears that these phenotypes arise by the inheritance of a variant allele of the ABO locus. Their cells react weakly when added to anti-B sera, and they have normal anti-A activity and an absence of anti-B in their sera. Additionally, all of the members tested had increased levels of cellular H substance and all of the affected secretor members of the family secreted normal amounts of both B and H substance. Transferase activity of the sera of these individuals confirmed the presence of the B-gene specific transferase.

Explore related subjects

ABO Blood-Group SystemAdultEpitopesFemaleGenesHumansMalePedigreeSalivaTransferasesCase ReportsJournal Article

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

A Simmons, J Twaitt. Another example of a B variant.. https://doi.org/10.1046/j.1537-2995.1975.15476034559.x

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed1979

beta-thromboglobulin in antecubital vein blood--the influence of age, sex and blood group.

Samples of blood for estimation of beta-thromboglobulin (B.T.G.) in normal subjects have been obtained both from blood donors at the end of their donation and from other volunteers by standard venepuncture. The former was a satisfactory method in males only. By standard venepuncture females have on average lower values than males and in the pre-menopausal age groups the difference is statistically significant. Mean values vary little up to 59 years after which they rise slowly but steadily. There is no significant difference in the mean B.T.G. values between the ABO blood groups.

ABO Blood-Group System↗
PubMed1979

Genetic polymorphisms and intrauterine development. Evidence of decreased heterozygosity in light-for-dates human newborn babies.

In 2 independent samples of low-birth-weight infants the proportion of females and homozygotes for a series of polymorphic systems was higher in light-for-dates than in preterm babies. The observation seems to give support to the hypothesis that homozygosity for 'normal' polymorphisms may decrease in general intrauterine growth rate. Since it is known that survival rate is strongly related to birth weight, a correlation between growth retardation and homozygosity may have a major role in the maintenance of such polimorphisms.

ABO Blood-Group System↗