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PubMed · 577356

Goniotomy and congenital glaucoma.

P M Moller
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Abstract

A survey is presented of the operative results obtained in 45 eyes suffering from congenital glaucoma, primarily operated on using micro-surgical techniques, either goniotomy as described by Worst, or trabeculotomy. Thirty-eight of the 45 eyes have, during an observation period of 1-10 years, average 5.5 years, a normal pressure of less than or equal to 18 mmHg measured using Draeger's technique. A relatively high frequency of recurrence has been found following an average observation period of 3.5 years in patients who were primarily normalized by Worst's goniotomy.

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Anterior ChamberFemaleFollow-Up StudiesGlaucomaHumansMaleMicrosurgeryRecurrenceTrabecular MeshworkJournal Article

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P M Moller. 1977. Goniotomy and congenital glaucoma.. https://pubmed.ncbi.nlm.nih.gov/577356/

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PubMed2007

Model of pulsatile-flow of aqueous humor through the iris-lens canal.

PURPOSE: To present a model of pulsatile-flow of aqueous humor from posterior (PC) to anterior chamber (AC) and to analyze the sensitivity of this novel model in detecting typical high risk conditions predisposing to pupillary block. METHODS: The model assumes noncontinuous flow of aqueous through the iris-lens canal. Aqueous that fills the canal will be ejected toward the AC-side of the canal at certain time intervals, and between 2 events of aqueous ejection there is no actual flow through this canal. Pupillary pumping rate (PPR) was calculated from the aqueous flow rate and the calculated volume of iris-lens canal. RESULTS: PPR values were generated by incorporating pupillary diameter (1 to 8 mm), aqueous flow rate (1 to 2.5 microL/min), and iris-lens canal width (0.5 to 2 mm) and height (3-9 microm) in numerical experimentation with the present model. PPR showed inverse dependence on iris-lens canal height and pupillary diameter and was directly proportional to aqueous flow rate, in agreement with the steady-flow model. However, contrary to the steady-flow model, PPR showed inverse dependence on iris-lens canal width and predicted the anticipated PC-AC pressure gradient changes at simulated light-dark transition in eyes of patients with clinically narrow angles and ultrasound biomicroscopy evidenced pupillary block. CONCLUSIONS: Upon the incorporation of real ultrasound biomicroscopy measurements in numerical experimentations with both models, the present pulsatile-flow model, contrary to the steady-flow model, showed good predictability of PC-AC pressure gradient changes in a typical condition predisposing to pupillary block.

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