PubMed · 584198
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L Parks. 1977. [Thoracic pain].. https://pubmed.ncbi.nlm.nih.gov/584198/
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Cardiovascular magnetic resonance imaging (MRI) has been in clinical use for barely a decade. During this relatively short period MRI has established itself as an important diagnostic instrument. MRI is an intrinsically three-dimensional, completely noninvasive technique. Its inherent high contrast between the flowing blood on the surrounding tissue make MRI an ideal diagnostic method for cardiovascular diseases, since it does not expose patients and staff to ionizing radiation and there is no need for the application of contrast media. The high spatial and excellent contrast resolution are the basis for the distinct delineation of the cardiovascular pathoanatomy. Infarcted and non-infarcted myocardium may be differentiated by the assessment of tissue relaxation times. With the use of Cine MRI, global and regional ventricular function may be quantified and bloodflow within cardiac chambers may be analyzed. Today's indications for cardiovascular MRI based on personal experience and the literature are presented.
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Raman spectra of highly calcified areas of human aorta were obtained using long wavelength excitation at 740 nm to minimize background fluorescence interference. Raman spectra resembling that of hydroxyapatite were obtained for segments of highly calcified aorta that were thawed frozen samples, from which the surface layer had been removed, or were dried. These are the first reported spectra obtained in air or in normal saline solution showing the hydroxyapatite peak in calcified plaque for samples which were untreated except for freezing, which is encouraging for the application of Raman spectroscopy as a method of detection of plaque during laser angioplasty. Spectra obtained from calcified aorta using excitation at 514.5 nm did not show evidence of the hydroxyapatite band because of the severe interference by background fluorescence generated at this wavelength.