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Scleropachynsis maculopathy.

H Conn·W R Green·Z C de la Cruz·A Hillis
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Abstract

To our knowledge, this is the first clinicopathologic report of a previously unrecognized maculopathy in which there is thickening and mucopolysaccharide deposition in the sclera subjacent to the macula. A healthy 50-year-old man had bilateral mottling of the retinal pigment epithelium (RPE) in the macular region. The left eye was enucleated because of a choroidal melanoma. Histopathologic examination disclosed a thickened sclera with abnormal collagen fibrils with diameters up to 5,800 A and compressed choroid. The overlying RPE had areas of hypopigmentation, hyperpigmentation, and hyperplasia and contained intracytoplasmic lipofuscin.

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ChoroidFluorescein AngiographyHumansMacula LuteaMacular DegenerationMaleMiddle AgedPigment Epithelium of EyeScleraStaining and LabelingCase ReportsJournal Article

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BibTeXRIS

H Conn, W R Green, Z C de la Cruz, A Hillis. 1982. Scleropachynsis maculopathy.. https://doi.org/10.1001/archopht.1982.01030030797015

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