[Alpha 2-macroglobulin: structure, properties and physiological role].

K N Veremeenko; O S Semeniuta; A I Kizim; K A Lobunets

PubMed · 6189273

[Alpha 2-macroglobulin: structure, properties and physiological role].

K N Veremeenko·O S Semeniuta·A I Kizim·K A Lobunets

Abstract

The paper is concerned with the results of recent researches devoted to studies of the structure, properties and physiological role of alpha 2-macroglobulin, one of main inhibitors of blood proteolytic enzymes. Data are presented on its primary and quaternary structure, mechanisms of interaction with proteinases. The role of alpha 2-macroglobulin in regulation of the activity of proteinases participating in blood coagulation, fibrinolysis, kininogenesis, immune reactions is shown. Possibilities of its application in medicine are discussed.

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Amino Acid Sequence Animals Blood Protein Electrophoresis Carbohydrates Diagnosis, Differential Hepatitis, Viral, Human Humans Neoplasms Protease Inhibitors Protein Conformation Radiation Injuries, Experimental Rats Substrate Specificity alpha-Macroglobulins English Abstract Journal Article Review

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K N Veremeenko, O S Semeniuta, A I Kizim, K A Lobunets. [Alpha 2-macroglobulin: structure, properties and physiological role].. https://pubmed.ncbi.nlm.nih.gov/6189273/

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