The lambda phage att site: functional limits and interaction with Int protein.

P L Hsu; W Ross; A Landy

doi:10.1038/285085a0

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The lambda phage att site: functional limits and interaction with Int protein.

P L Hsu·W Ross·A Landy

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Abstract

Site specific integrative recombination of bacteriophage lambda involves unequal partners. The minimal phage att site is composed of approximately 240-base pairs and four distinct binding sites for Int protein, at least three of which are crucial for function. This 'donor site' recombines efficiently with a smaller 'recipient site' that lacks the extensive interactions with Int protein.

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Attachment Sites, Microbiological Bacteriophage lambda Base Sequence DNA Helicases DNA, Bacterial DNA, Superhelical DNA, Viral Escherichia coli Integrases Lysogeny Plasmids Viral Proteins Journal Article Research Support, U.S. Gov't, P.H.S.

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P L Hsu, W Ross, A Landy. 1980-05-08. The lambda phage att site: functional limits and interaction with Int protein.. https://doi.org/10.1038/285085a0

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