Thymus cell variations in AKR leukemia.

R M Zucker; D M Helfman; A M Tershakovec

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PubMed · 629437

Thymus cell variations in AKR leukemia.

R M Zucker·D M Helfman·A M Tershakovec

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Abstract

The thymus cells from spontaneous and 1st generation AKR leukemic mice were investigated, using electronic cell-volume distributions. The growth pattern of thymus cells in the mice with transplanted leukemic cells varied with the type of donor cells injected. After the transplantation of leukemic cells into 2 month-old recipients, the cortex of thymus decreased in size and medulla of thymus enlarged. The thymus underwent atrophy next, followed by a proliferation of the large-sized cells (greater than channel 40, 136 micrometer3). The electronic cell-volume distributions of the thymus cells from the spontaneous leukemic mice encompass the distributions of thymus cells during the growth of the transplanted leukemia.

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Animals Bone Marrow Leukemia, Experimental Lymph Nodes Mice Mice, Inbred AKR Neoplasm Transplantation Spleen Thymus Gland Transplantation, Homologous Journal Article Research Support, U.S. Gov't, P.H.S.

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R M Zucker, D M Helfman, A M Tershakovec. 1978. Thymus cell variations in AKR leukemia.. https://pubmed.ncbi.nlm.nih.gov/629437/

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