PubMed · 6338446
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H A Goldstein. 1983. Bone scintigraphy.. https://pubmed.ncbi.nlm.nih.gov/6338446/
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The authors report four cases of spinal cord compression (three at cervical level and one at dorsal level) due to vertebral osteosclerosis secondary to chronic fluoride intoxication. Roentgenograms showed typical diffuse densification of vertebral bodies, calcifications of bony insertions of many ligaments, discs and interosseous membranes. Urinary fluoride was markedly increased in two cases. In the other two cases the bone biopsy was suggestive of skeletal fluorosis. Spinal computed tomography showed severe cord compression due to posterior osteophytes. Good improvement was observed after surgical decompression in one case. Fluorosis was described as a consequence of endemic exposure to high fluoride content in soil and natural ground water in North Africa. Fluorotic myelopathy was due to bone excrescences mainly affecting the spine.
A PC software program with a graphical users platform was developed which enables the transfer of bone scintigraphy results to vectorgraphy-based skeleton images, and to implement a fully automatic anatomical localization definition of lesions. Documentation of the results is made possible by a complete, conventional structured medical letter. Additional information such as data on the patient, diagnostic methods and results, sacro-iliacal indexes, recommendations and remarks can be added to the scintigrams. By implementation of a database and PCX-interface, the system is open.