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PubMed · 6387574

Bone structure, composition, and mineralization.

A L Boskey·A S Posner
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Abstract

Bone structure and function are dependent on complex interactions between cells, matrix, cell-derived factors, and systemic factors. The deposition of mineral in bone, which enables the skeleton to function properly, is described as a four-step process of matrix modification, crystal nucleation, crystal growth, and remodeling. Insight into the function of bone components in the mineralization process is provided by in vitro studies and analysis of abnormal calcifications.

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AnimalsBone DevelopmentBone MatrixBone Morphogenetic ProteinsBone ResorptionBone and BonesCalcium-Binding ProteinsCollagenExtracellular MatrixGrowth SubstancesHumansHydroxyapatitesMicroscopy, ElectronMineralsOsteoblastsOsteocalcinOsteoclastsOsteocytesOsteogenesisPhosphoproteinsProteinsProteolipidsJournal ArticleResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, P.H.S.Review

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A L Boskey, A S Posner. 1984. Bone structure, composition, and mineralization.. https://pubmed.ncbi.nlm.nih.gov/6387574/

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