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PubMed · 641043

Concentration-dependent conformational transition of alpha-elastin in aqueous solution.

A M Tamburro·V Guantieri·D Daga-Gordini·G Abatangelo
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Abstract

Circular dichroism measurements on aqueous solutions of alpha-elastin have given evidence of beta-bend structure at elevated concentrations. When Ca2+ was added, the concentration-dependent conformational transition was somewhat inhibited and the binding of the metal ion was shown, by means of equilibrium dialysis, to be essentially independent from alpha-elastin concentration in the range of 1 to 10 mg/ml. The results obtained are discussed in connection with the elasticity and calcification of elastin.

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A M Tamburro, V Guantieri, D Daga-Gordini, G Abatangelo. 1978-05-10. Concentration-dependent conformational transition of alpha-elastin in aqueous solution.. https://pubmed.ncbi.nlm.nih.gov/641043/

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